L-Amino Acids Promote Calcitonin Release via a Calcium-Sensing Receptor: Gq/11-Mediated Pathway in Human C-Cells

H Mun, KM Leach, AD Conigrave - Endocrinology, 2019 - academic.oup.com
… on calcitonin-secreting thyroid C-cells and thereby induce Ca … basal Ca 2+ o concentration
of 0.5 mM, we observed a slow, … 2, have been linked to inactivating and activating mutations of …

[图书][B] The calcium-sensing receptor as a mineral sensor

PP Centeno - 2019 - search.proquest.com
… The work discussed in this thesis concludes my PhD in … gland, bone, calcitonin-secreting
thyroidal cells, and kidney, but … eral ions and ensuring that calcium-phosphate product (Ca x P) …

[图书][B] Applied animal endocrinology

EJ Squires - 2024 - books.google.com
… and on the understanding that any person who acts upon it, or otherwise changes their …
-associated nuclease cell autonomous sex identity calcium-sensing receptor chloramphenicol …

[HTML][HTML] Reduced affinity of calcium sensing-receptor heterodimers and reduced mutant homodimer trafficking combine to impair function in a model of familial …

X Wang, J Lundblad, SM Smith - PloS one, 2022 - journals.plos.org
cell membrane and still able to detect changes in [Ca 2+ ] o . We tested this hypothesis by
measuring intracellular [Ca 2+ ] in HEK cells … and then decreased slowly during the application …

Ca2+ Channel Blockers

J Striessnig, NJ Ortner - Encyclopedia of Molecular Pharmacology, 2022 - Springer
… Once the cell repolarizes, inactivated channels return to the … Instead, DHPs with slower
onset and longer duration of action (… calcium levels, such as the thyroidal calcitonin-secreting C-…

Pediatric parathyroid disease

R Jamshidi, JC Egan - Seminars in Pediatric Surgery, 2020 - Elsevier
… that become the calcitonin-secreting parafollicular C cells. The … the calcium-sensing receptor
(CaSR) due to an inactivating … , vitamin D, and calcitriol, but PTH analogs are gradually

Ca2+-Sensing Receptor (CaSR)

G Valenti - Encyclopedia of Molecular Pharmacology, 2022 - Springer
… Once the cell repolarizes, inactivated channels return to the … Instead, DHPs with slower
onset and longer duration of action (… calcium levels, such as the thyroidal calcitonin-secreting C-…

Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis Due to CLDN16 Gene Mutations: Novel Findings in Two Cases with Diverse Clinical Features

M Eltan, Z Yavas Abali, A Turkyilmaz, I Gokce… - Calcified tissue …, 2022 - Springer
… chief cells of parathyroid gland, calcitonin secreting C cells of … on PTH secretion; mild
hypomagnesemia lead to inactivation … at least one allele have a slower progression to CKD (mean …

Carcinoma Showing Thymus-Like Differentiation (CASTLE)

C Eloy - Endocrine Pathology, 2022 - Springer
… , and in some animals, calcitonin-secreting cells are located … in the calcium concentration are
sensed through the calcium-… have to bypass liver inactivation and directly enter the systemic …

Chromogranin

AM Chiaravalli - Endocrine Pathology, 2022 - Springer
… , and in some animals, calcitonin-secreting cells are located … in the calcium concentration are
sensed through the calcium-… have to bypass liver inactivation and directly enter the systemic …